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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL1
All Species:
23.33
Human Site:
T556
Identified Species:
39.49
UniProt:
Q15111
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15111
NP_006217.3
1095
122728
T556
D
V
L
E
G
E
V
T
D
E
D
E
E
A
E
Chimpanzee
Pan troglodytes
XP_001169560
1095
122728
T556
D
V
L
E
G
E
V
T
D
E
D
E
E
A
E
Rhesus Macaque
Macaca mulatta
XP_001089483
1095
122754
T556
D
V
L
E
G
E
V
T
D
E
D
E
E
A
E
Dog
Lupus familis
XP_536020
1096
122535
T557
D
V
L
E
G
E
V
T
D
E
D
E
E
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3USB7
1096
122654
T557
D
L
L
E
G
E
V
T
D
E
D
E
E
A
E
Rat
Rattus norvegicus
Q62688
1096
122754
T557
D
L
L
E
G
E
V
T
D
E
D
E
E
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
G513
D
V
T
D
E
D
E
G
A
E
M
S
Q
R
V
Chicken
Gallus gallus
Q2VRL0
637
72514
F167
N
H
P
L
C
D
Y
F
I
S
S
S
H
N
T
Frog
Xenopus laevis
Q32NH8
758
87399
L288
F
N
V
A
H
E
Q
L
Y
Q
D
M
M
Q
P
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
D314
D
H
T
H
V
Y
Q
D
M
S
K
P
L
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
E521
P
E
A
A
A
A
A
E
G
A
A
E
G
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
V521
P
D
T
D
S
G
E
V
S
E
E
D
D
S
L
Sea Urchin
Strong. purpuratus
XP_001178766
684
77475
Y214
R
I
D
E
D
L
S
Y
L
P
S
P
H
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
L399
A
S
S
H
N
T
Y
L
L
G
K
Q
I
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
98.7
96.4
N.A.
94.3
94.1
N.A.
62.9
21.7
24.7
27.9
N.A.
20
N.A.
39
35.8
Protein Similarity:
100
100
99.2
98.5
N.A.
96.6
96.6
N.A.
77.1
34.8
40.4
42.3
N.A.
40.2
N.A.
59.4
48.1
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
0
13.3
13.3
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
13.3
26.6
13.3
N.A.
6.6
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
15
8
8
8
0
8
8
8
0
0
58
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
58
8
8
15
8
15
0
8
43
0
50
8
8
8
0
% D
% Glu:
0
8
0
50
8
50
15
8
0
58
8
50
43
0
50
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
43
8
0
8
8
8
0
0
8
8
8
% G
% His:
0
15
0
15
8
0
0
0
0
0
0
0
15
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% K
% Leu:
0
15
43
8
0
8
0
15
15
0
0
0
8
0
15
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
8
8
0
0
% M
% Asn:
8
8
0
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
15
0
8
0
0
0
0
0
0
8
0
15
0
0
8
% P
% Gln:
0
0
0
0
0
0
15
0
0
8
0
8
8
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
8
8
0
8
0
8
0
8
15
15
15
0
8
0
% S
% Thr:
0
0
22
0
0
8
0
43
0
0
0
0
0
0
8
% T
% Val:
0
36
8
0
8
0
43
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
15
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _